Author Topic: Coronavirus thread  (Read 335717 times)

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Offline k a rl h e nn i ng

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Re: Coronavirus thread
« Reply #7240 on: May 05, 2022, 07:04:33 AM »
Karl, I wish you a speedy recovery!

Thanks! Warmly appreciated!
Karl Henning, Ph.D.
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Offline foxandpeng

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Re: Coronavirus thread
« Reply #7241 on: May 05, 2022, 07:11:42 AM »
Thanks, gents. Mostly feeling like a damp dishrag.

Recover quickly, sir!
“A quiet secluded life in the country, with the possibility of being useful to people ... then work which one hopes may be of some use; then rest, nature, books, music, love for one's neighbour — such is my idea of happiness"

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Offline k a rl h e nn i ng

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Re: Coronavirus thread
« Reply #7242 on: May 05, 2022, 08:00:19 AM »
Recover quickly, sir!

Thanks! Feeling a shade better today: The Paxlovid seems to be doing its job!
Karl Henning, Ph.D.
Composer & Clarinetist
Boston MA
http://www.karlhenning.com/
[Matisse] was interested neither in fending off opposition,
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His only competition was with himself. — Françoise Gilot

Offline steve ridgway

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Re: Coronavirus thread
« Reply #7243 on: May 05, 2022, 08:45:12 PM »
Good news!

Offline k a rl h e nn i ng

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Re: Coronavirus thread
« Reply #7244 on: May 06, 2022, 05:34:28 AM »
Thanks!
Karl Henning, Ph.D.
Composer & Clarinetist
Boston MA
http://www.karlhenning.com/
[Matisse] was interested neither in fending off opposition,
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His only competition was with himself. — Françoise Gilot

Offline Spotted Horses

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Re: Coronavirus thread
« Reply #7245 on: May 06, 2022, 05:34:49 AM »
Thanks! Feeling a shade better today: The Paxlovid seems to be doing its job!

Beware!

Paxlovid Mouth Is Real—And Gross
https://www.theatlantic.com/health/archive/2022/05/pfizer-paxlovid-covid-pill-side-effects/629772/

Offline k a rl h e nn i ng

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Re: Coronavirus thread
« Reply #7246 on: May 06, 2022, 06:11:38 AM »
Thanks. My friend Peter alluded to this. Pleased to report no such experience (as yet?) Today is Day 3 of the course. The "grapefruit" mentions have me associatively recalling that my doctor bade me stop use of my statin during the Paxlovid course (since my taking the statin, I've been completely forbidden grapefruit juice, as there is an interaction.
Karl Henning, Ph.D.
Composer & Clarinetist
Boston MA
http://www.karlhenning.com/
[Matisse] was interested neither in fending off opposition,
nor in competing for the favor of wayward friends.
His only competition was with himself. — Françoise Gilot

Offline Que

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Re: Coronavirus thread
« Reply #7247 on: May 07, 2022, 03:51:20 AM »
Infection rates of Omicron BA4 and BA5 are picking up in the Netherlands.

Assessment on the basis of the situation in SA:

https://www.nature.com/articles/d41586-022-01240-x



Offline krummholz

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Re: Coronavirus thread
« Reply #7248 on: May 07, 2022, 06:18:00 AM »
Thanks! Feeling a shade better today: The Paxlovid seems to be doing its job!

Glad to hear this, Karl! Hope the upward trend continues...

Offline k a rl h e nn i ng

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Re: Coronavirus thread
« Reply #7249 on: May 07, 2022, 08:32:48 AM »
Glad to hear this, Karl! Hope the upward trend continues...

Thanks! Gradual improvement, still low-ish energy.
Karl Henning, Ph.D.
Composer & Clarinetist
Boston MA
http://www.karlhenning.com/
[Matisse] was interested neither in fending off opposition,
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His only competition was with himself. — Françoise Gilot

Offline steve ridgway

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Re: Coronavirus thread
« Reply #7250 on: May 07, 2022, 08:45:15 AM »
Improvement is good. :)

Offline MusicTurner

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Re: Coronavirus thread
« Reply #7251 on: May 11, 2022, 07:48:46 PM »
North Korea has now confirmed its 'first cases' of the corona virus ...
« Last Edit: May 11, 2022, 08:03:14 PM by MusicTurner »

Offline steve ridgway

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Re: Coronavirus thread
« Reply #7252 on: May 12, 2022, 01:39:47 AM »
North Korea has now confirmed its 'first cases' of the corona virus ...

Perhaps they’ll wipe it out by nuking Pyongyang. >:D

Offline k a rl h e nn i ng

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Re: Coronavirus thread
« Reply #7253 on: May 14, 2022, 06:42:35 AM »
A new Omicron variant, BA.2.12.1, has taken over in Massachusetts. Here’s what you need to know.

By Kay Lazar Globe Staff, Updated May 13, 2022, 8:45 a.m.

The virus that causes COVID-19 didn’t change much in the early days of the pandemic. Then the number of mutations started increasing, and scientists began using an alphabet soup of letters and numbers to distinguish them.

But nothing prepared them for the dizzying array of strains that the mighty Omicron variant has been spitting out.

As one of the newest Omicron variants, BA.2.12.1, overtakes its predecessors, here’s what you need to know.

First things, first. The original Omicron variant, called B.1.1.529, emerged in South Africa last year and spread quickly around the world. By late January, another Omicron subvariant, BA.1.1, already was dominant in the United States.

Fast forward to this spring. The BA.2.12.1 subvariant from the fast-moving Omicron lineage was first detected in New York in March, along with its sibling, BA.2.1. These two subvariants are estimated to spread 23 percent to 27 percent faster than their predecessor, the BA.2 variant. Consider that in early March, the Centers for Disease Control and Prevention reported that BA.2 accounted for about 26 percent of all cases in the US, and BA.2.12.1 accounted for less than 1 percent. By May 7, BA.2 had roughly doubled its prevalence, to about 56 percent of all cases — but BA.2.12.1 had exploded and now accounts for 43 percent of the country’s COVID cases. (It’s about 40 percent of New England cases, and the Broad Institute of MIT and Harvard estimates that it has taken over in Massachusetts, accounting for nearly 70 percent of cases.)

Will BA.2.12.1 elbow out its sibling for top spot?

Scientists tracking Omicron say that’s already happening. Yet its extraordinary speed, fueling another rapid rise in cases, is puzzling researchers because its structure is not all that different from its predecessor’s. “It’s almost like having somebody who runs a 2:30 marathon changing their sneakers and all of a sudden running a two-hour marathon. It doesn’t make sense,” said Dr. Jacob Lemieux, an infectious disease specialist at Massachusetts General Hospital, who is also coleader of the viral variants program at the Massachusetts Consortium on Pathogen Readiness.

Is BA.2.12.1 better at evading immunity?

Yes, it appears it has an increased capacity to evade antibodies triggered by a previous Omicron infection and vaccination, according to recent research by Chinese scientists that has not been peer reviewed. Dr. Pedro Piedra, a professor of molecular virology and microbiology at Baylor College of Medicine in Houston, compares these virus variants to a leopard that can change its spots to help it avoid detection.

“As these viruses go through the population once, it becomes harder to reinfect the population that already has a level of protection against that variant,” he said. “What we are seeing is these rapid changes that are enough for this variant to take a foothold and cause infection.”

What about the level of illness from BA.2.12.1?

While this latest subvariant doesn’t appear to be causing the flood of hospitalizations that the original Omicron wave did over the winter, hospitalizations are slowly rising again as cases mount in Massachusetts.

“I and many other people had expected that as treatments become more available, as vaccinations are more widespread, we would see a decoupling of the case counts and hospitalizations and we have to a large extent,” Lemieux said. “However it hasn’t been a complete decoupling that was hoped for. So we will have to keep a close eye on the hospitalization count.”

Are there yet more Omicron variants out there?

Yes. Meet BA.4 and BA.5, the newest offshoots identified by scientists in South Africa. The two subvariants have rapidly replaced Omicron’s BA.2 line, reaching more than 50 percent of sequenced cases in South Africa from the first week of April 2022 onward, a team of researchers there recently reported in a study that has not been peer reviewed. The scientists also reported “early signs” of rising hospital admissions in some of the country’s provinces. They said there are signs BA.4 and BA.5 may be even more wily about evading immunity. As far as causing more severe disease, they said the jury is still out.

Are BA.4 and BA.5 in the US?

Yes. Outbreak.info, a database that tracks variants worldwide, reports that BA.4 was first detected in the US in March, and has since been pinpointed in at least 17 states, including Massachusetts. But it still accounts for less than 1 percent of the samples sequenced in the country. According to the database, BA.5 has shown up in at least 13 states, including Massachusetts, as of mid-April, but it has a tiny presence here, accounting for fewer than 1 percent of sequenced samples.
Karl Henning, Ph.D.
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[Matisse] was interested neither in fending off opposition,
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His only competition was with himself. — Françoise Gilot

Offline k a rl h e nn i ng

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Re: Coronavirus thread
« Reply #7254 on: May 14, 2022, 06:44:39 AM »
11 of 14 Mass. counties now have high levels of COVID-19, CDC reports; indoor masking recommended
Karl Henning, Ph.D.
Composer & Clarinetist
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[Matisse] was interested neither in fending off opposition,
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His only competition was with himself. — Françoise Gilot

Offline Madiel

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Re: Coronavirus thread
« Reply #7255 on: May 14, 2022, 12:57:39 PM »
Australia is apparently top of the world at getting infected right now. How things have changed.

And over in New Zealand, Jacinda Ardern has it.
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Re: Coronavirus thread
« Reply #7256 on: May 14, 2022, 02:21:39 PM »
Thanks! Gradual improvement, still low-ish energy.

Gradual improvement sounds promising.  :)
Hope you continue at least in this way or still better with faster improvement!
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Offline k a rl h e nn i ng

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Re: Coronavirus thread
« Reply #7257 on: May 14, 2022, 02:54:43 PM »
Gradual improvement sounds promising.  :)
Hope you continue at least in this way or still better with faster improvement!

Warm thanks!
Karl Henning, Ph.D.
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Boston MA
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[Matisse] was interested neither in fending off opposition,
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His only competition was with himself. — Françoise Gilot

Offline Dry Brett Kavanaugh

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Re: Coronavirus thread
« Reply #7258 on: May 18, 2022, 02:03:42 PM »
Clapton.